Recently, the team led by Prof. HUANG Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS) developed a novel biosensor based on aptamer-combined surface-enhanced Raman spectroscopy (SERS) to achieve the inflammatory microRNA-122 (miR-122) detection in cell-s...
Recently, a potent and selective enhancer of zeste homolog 2 (EZH2) inhibitor IHMT-EZH2-115 was discovered by a team led by Prof. LIU Qingsong from Hefei Institutes of Physical Science, Chinese Academy of Sciences, for the treatment of B-cell lymphomas.
Although many diseases have no obvious symptoms in the early diagnosis, it’s proved that human body would defend itself through the immune system in the early stage of disease. Corresponding signals, such as sweat, urine, tears, blood, exhaled breath, are usually sent out for early warning.
Human telomeric DNA consists of a tandem array of the G-rich repeat unit d(GGGTTA). A four-stranded helical structure adopted by G-rich sequences was named G-quadruplex (GQ) under physiological condition. The final 3'-terminal residue of the telomeric DNA G-overhang is inherently less precise.
Haematococcus pluvialis (H. pluvialis) can produce natural astaxanthin which has strong antioxidant capacity. How to improve the astaxanthin content of H. pluvialis is a hot topic of current research.